Description
Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961) Cholera enterotoxin subunit B Protein, His Tag (MALS verified) | GHB-V52H3-50ug| Gentaur Distribution US, UK & Europe
Cholera toxin is protein complex secreted by the bacterium Vibrio cholerae. It is responsible for the massive, watery diarrhea characteristic of cholera infection. The B subunit of cholera toxin (CtxB) binds to a GM1-ganglioside receptor, a ubiquitous glycolipid cell surface receptor. This binding is widely accepted to initiate toxin action by triggering uptake and delivery of the toxin A subunit into cells. The beta chain has no toxic activity by itself. The holotoxin consists of a pentameric ring of B subunits whose central pore is occupied by the A subunit. The A subunit contains two chains, A1 and A2, linked by a disulfide bridge.
Source: Vibrio cholerae serotype O1 Cholera enterotoxin subunit B, His Tag (GHB-V52H3) is expressed from human 293 cells (HEK293). It contains AA Thr 22 - Asn 124 (Accession # P01556).
Format: Powder.
Tag: C-10×His.
Expression System: HEK293.
Expression Region: Thr 22 - Asn 124.
Conjugate: Unconjugated.
Molecular Weight: 13.5 kDa.
Characteristics: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 13.5 kDa. The protein migrates as 16-17 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Purity: 95%.
Buffer: PBS, pH7.4.
Storage Conditions: -20℃.
Shipping Conditions: RT
