Description
VEGFR2 / Flk-1 / KDR3 / CD309(KDR657), CF647 conjugate, 0.1mg/mL Antibody | BNC470657-100| Gentaur Distribution US, UK & Europe
Summary.: CD309, also known as VEGF-R2, KDR3, and Flk-1 (mouse), is a type I transmembrane glycoprotein. It is a member of the CSF-1/PDGF receptor family of type III tyrosine kinase receptors. Human VEGF-R2 is mainly expressed by endothelial cells, embryonic tissues, and megakaryocytes. It plays an important role in the regulation of angiogenesis, vasculogenesis, and vascular permeability. The ligands of VEGF-R2 include VEGF-A, VEGF-C, VEGF-D, and VEGF splice isoforms. Ligation of VEGF-R2 with its ligands results in the receptor dimerization and auto-phosphorylation, stimulating endothelial cell proliferation and migration.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors. .
Conjugate: CF647.
Storage Buffer: PBS, 0.1% BSA, 0.05% azide.
Storage Temperature: 2°C to 8°C.
Application: .
Stability: Stable at room temperature or 37°C (98°F) for 7 days.
