VE Cadherin Antibody (Intracellular Junction Marker) | F48144-0.08ML

VE Cadherin Antibody (Intracellular Junction Marker) | F48144-0.08ML | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide

Format: Antigen affinity purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Species Reactivity: Human

Application: WB, FACS, ELISA

Buffer: N/A

Limitation: This VE Cadherin antibody is available for research use only.

Purity: Antigen affinity

Description: CDH5 is a classical cadherin from the cadherin superfamily and is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. It is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Functioning as a classic cadherin by imparting to cells the ability to adhere in a homophilic manner, the protein may play an important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions.

Immunogen: A portion of amino acids 106-134 from the human protein was used as the immunogen for this VE Cadherin antibody.

Storage: Aliquot the VE Cadherin antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.