VCAM-1 Antibody | V2922SAF-100UG

VCAM-1 Antibody | V2922SAF-100UG | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: 1 mg/ml in 1X PBS; BSA free, sodium azide free

Format: Purified

Clone: 1.4C3

Host Animal: Mouse

Clonality: Monoclonal (mouse origin)

Species Reactivity: Human

Application: FACS, IF, IHC-P

Buffer: N/A

Limitation: This VCAM-1 antibody is available for research use only.

Purity: Protein G affinity chromatography

Description: Recognizes a protein of 110kDa, identified as CD106 (also known as vascular cell adhesion molecule-1 (VCAM-1), L1CAM and INCAM-100). It is a member of the Ig superfamily of adhesion molecules and is expressed at high levels on cytokine stimulated vascular endothelial cells, and at minimal levels on un-stimulated endothelial cells. It is also present on follicular and inter-follicular dendritic cells of lymph nodes, myoblasts, and some macrophages. VCAM-1 serves as a ligand for leukocyte integrin (VLA-4 or CD49d/CD29) and mediates cell adhesion of leukocytes to activated endothelium. It plays a role in various immunological and inflammatory responses.

Immunogen: Stimulated human umbilical vein endothelial cells (HUVEC) were used as the immunogen for the VCAM-1 antibody.

Storage: Store the VCAM-1 antibody at 2-8oC (with azide) or aliquot and store at -20 °C or colder (without azide).