UVRAG Antibody | F54723-0.08ML

UVRAG Antibody | F54723-0.08ML | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide

Format: Purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Species Reactivity: Human, Mouse

Application: IF, IHC-P, WB

Buffer: N/A

Limitation: This UVRAG antibody is available for research use only.

Purity: Purified

Description: UVRAG complements the ultraviolet sensitivity of xeroderma pigmentosum group C cells and encodes a protein with a C2 domain. The protein activates the Beclin1-PI(3)KC3 complex, promoting autophagy and suppressing the proliferation and tumorigenicity of human colon cancer cells. Chromosomal aberrations involving this gene are associated with left-right axis malformation and mutations in this gene have been associated with colon cancer.

Immunogen: A portion of amino acids 666-699 from the human protein was used as the immunogen for the UVRAG antibody.

Storage: Aliquot the UVRAG antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.