Uroplakin 1B Antibody / UPK1B | V8153SAF-100UG

Uroplakin 1B Antibody / UPK1B | V8153SAF-100UG | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: 1 mg/ml in 1X PBS; BSA free, sodium azide free

Format: Purified

Clone: UPK1B/3273

Host Animal: Mouse

Clonality: Monoclonal (mouse origin)

Species Reactivity: Human

Application: IHC-P

Buffer: N/A

Limitation: This Uroplakin 1B antibody is available for research use only.

Purity: Protein G affinity chromatography

Description: The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is found in the asymmetrical unit membrane (AUM) where it can form a complex with other transmembrane 4 superfamily proteins. It may play a role in normal bladder epithelial physiology, possibly in regulating membrane permeability of superficial umbrella cells or in stabilizing the apical membrane through AUM/cytoskeletal interactions. UPK1B is expressed by terminally differentiated urothelial cells.

Immunogen: A recombinant human partial protein (amino acids 109-229) was used at the immunogen for this Uroplakin 1B antibody.

Storage: Store the Uroplakin 1B antibody at 2-8oC (with azide) or aliquot and store at -20 °C or colder (without azide).