UNC13D Polyclonal Antibody | E-AB-64476

UNC13D Polyclonal Antibody | E-AB-64476 | Gentaur US, UK & Europe Disrtribition

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Application: WB

Research Area: Immunology

Background: This gene encodes a protein that is a member of the UNC13 family, containing similar domain structure as other family members but lacking an N-terminal phorbol ester-binding C1 domain present in other Munc13 proteins. The protein appears to play a role in vesicle maturation during exocytosis and is involved in regulation of cytolytic granules secretion. Mutations in this gene are associated with familial hemophagocytic lymphohistiocytosis type 3, a genetically heterogeneous, rare autosomal recessive disorder.

Lead Time: 7~10 days

Concentration: 1 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Recombinant fusion protein of human UNC13D (NP_954712.1).

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification: Affinity purification

Dilution: WB 1:1000-1:2000

Conjugation: Unconjugated

Calculated Molecular Weight: 41 kDa/123 kDa/128 kDa

Observed Molecular Weight: 123 kDa

Clonality: N/A