Description
UHRF1 Antibody | F51386-0.08ML | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide
Format: Antigen affinity purified
Clone: N/A
Host Animal: Rabbit
Clonality: Polyclonal (rabbit origin)
Species Reactivity: Human
Application: FACS, IF, WB, ELISA
Buffer: N/A
Limitation: This UHRF1 antibody is available for research use only.
Purity: Antigen affinity
Description: UHRF1 is a member of a subfamily of RING-finger type E3 ubiquitin ligases. The protein binds to specific DNA sequences, and recruits a histone acetylase to regulate gene expression. Its expression peaks at late G1 phase and continues during G2 and M phases of the cell cycle. It plays a major role in the G1/S transition by regulating topoisomerase IIalpha and retinoblastoma gene expression, and functions in the p53-dependent DNA damage checkpoint.
Immunogen: A portion of amino acids 229-257 from the human protein was used as the immunogen for this UHRF1 antibody.
Storage: Aliquot the UHRF1 antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.
