UGT1A10 Antibody / UDP-glucuronosyltransferase 1A10 | RQ7048

UGT1A10 Antibody / UDP-glucuronosyltransferase 1A10 | RQ7048 | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: 0.5mg/ml if reconstituted with 0.2ml sterile DI water

Format: Antigen affinity purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Species Reactivity: Human

Application: WB, FACS

Buffer: Lyophilized from 1X PBS with 2% Trehalose

Limitation: This UDP-glucuronosyltransferase 1A10 antibody is available for research use only.

Purity: Antigen affinity purified

Description: UDP-glucuronosyltransferase 1-10 is an enzyme that in humans is encoded by the UGT1A10 gene. This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. The enzyme encoded by this gene has glucuronidase activity on mycophenolic acid, coumarins, and quinolines.

Immunogen: Amino acids HIVHLEDHLFCQYLFRNALEIASEILQ were used as the immunogen for the UDP-glucuronosyltransferase 1A10 antibody.

Storage: After reconstitution, the UDP-glucuronosyltransferase 1A10 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20 °C. Avoid repeated freezing and thawing.