UBF Antibody (Upstream binding factor 1) | F42275-0.08ML

UBF Antibody (Upstream binding factor 1) | F42275-0.08ML | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide

Format: Antigen affinity purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Species Reactivity: Human

Application: WB, ELISA

Buffer: N/A

Limitation: This UBF antibody is available for research use only.

Purity: Antigen affinity

Description: Upstream binding factor (UBF) is a transcription factor required for expression of the 18S, 5.8S, and 28S ribosomal RNAs, along with SL1 (a complex of TBP and multiple TBP-associated factors or 'TAFs'). Two UBF polypeptides, of 94 and 97 kD, exist in the human. UBF is a nucleolar phosphoprotein with both DNA binding and transactivation domains. Sequence-specific DNA binding to the core and upstream control elements of the human rRNA promoter is mediated through several HMG boxes.

Immunogen: A portion of amino acids 631-660 from the human protein was used as the immunogen for this UBF1 / UBF antibody.

Storage: Aliquot the UBF antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.