Description
UBC9 Antibody | R31382 | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: 0.5mg/ml if reconstituted with 0.2ml sterile DI water
Format: Antigen affinity purified
Clone: N/A
Host Animal: Rabbit
Clonality: Polyclonal (rabbit origin)
Species Reactivity: Human, Mouse, Rat
Application: WB
Buffer: N/A
Limitation: This UBC9 antibody is available for research use only.
Purity: Antigen affinity
Description: SUMO-conjugating enzyme UBC9, also called UBE2I, is a protein that in humans is encoded by the UBE2I gene. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. UBE2I could fully complement the mutant phenotype of a yeast ubc9 mutant strain. This gene may play a similar role via interaction with WT1, which is able to impose a block to cell cycle progression in eukaryotic cells. Additionally, it could support the growth of yeast ubc9 temperature-sensitive mutants at nonpermissive temperatures, indicating that the gene is a functional homolog of yeast ubc9. The protein is specifically associated with FHIT, such as FHIT may be involved in cell cycle control through its interaction with UBE2I.
Immunogen: An amino acid sequence from the C-terminus of human UBC9/UBE2I (IKQILLGIQELLNE) was used as the immunogen for this UBC9 antibody (100% homologous in human, mouse and rat).
Storage: After reconstitution, the UBC9 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20 °C. Avoid repeated freezing and thawing.
