UBC9 Antibody | F40817-0.4ML

UBC9 Antibody | F40817-0.4ML | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide

Format: Purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Species Reactivity: Human

Application: WB, IHC, ELISA

Buffer: N/A

Limitation: This UBC9 antibody is available for research use only.

Purity: Purified

Description: UBE2I (Ubc9) is a member of the E2 family and is specific for the conjugation of SUMO to a variety of target proteins. SUMO conjugation to target proteins is mediated by a different, but analogous, pathway to ubiquitinylation. This E2 is unusual in that it interacts directly with protein substrates that are modified by sumoylation, and may play a role in substrate recognition. UBE2I can mediate the conjugation of SUMO-1 to a variety of proteins including RanGAP1, I?B?, and PML without the requirement of an E3 ligase. UBE2I is essential for nuclear architecture and chromosome segregation.

Immunogen: A portion of amino acids 1-30 from the human protein was used as the immunogen for this UBC9 antibody.

Storage: Aliquot the UBC9 antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.