UACA Antibody | V2797-100UG

UACA Antibody | V2797-100UG | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide

Format: Purified

Clone: UACA/1222

Host Animal: Mouse

Clonality: Monoclonal (mouse origin)

Species Reactivity: Human, Mouse

Application: WB

Buffer: N/A

Limitation: This UACA antibody is available for research use only.

Purity: Protein G affinity chromatography

Description: UACA (Uveal Autoantigen with Coiled-coil domains and Ankyrin repeats) is a 1,416 amino acid nuclear membrane protein. It was originally identified as an autoantigen in patients with panuveitis, a characteristic of Vogt-Koyanagi-Harada disease, and in patients with Graves' disease. UACA was also later identified as Nucling, an mRNA differentially expressed in F9 embryonal carcinoma cells during cardiac muscle differentiation. UACA appears to function as a pro-apoptotic protein that recruits the apaf-1-pro-caspase-9 complex for the induction of apoptosis to mediate the cell-death pathway.

Immunogen: Recombinant human protein was used as the immunogen for the UACA antibody.

Storage: Store the UACA antibody at 2-8oC (with azide) or aliquot and store at -20 °C or colder (without azide).