Type I Cytokeratin Antibody (CK10/14/15/16/19) | V8658SAF-100UG

Type I Cytokeratin Antibody (CK10/14/15/16/19) | V8658SAF-100UG | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: 1 mg/ml in 1X PBS; BSA free, sodium azide free

Format: Purified

Clone: KRTL/4440R

Host: Rabbit

Clonality: Recombinant Rabbit Monoclonal

Isotype: Rabbit IgG, kappa

Species Reactivity: Human

Application: IHC-P

Application Details: Immunohistochemistry (FFPE): 1-2ug/ml for 30 minutes at RT

Application Note: Optimal dilution of the recombinant Type I Cytokeratin antibody should be determined by the researcher.

Purity: Protein A affinity chromatography

Description: The keratins are the typical intermediate filament proteins of epithelia, showing an outstanding degree of molecular diversity. Heteropolymeric filaments are formed by pairing of type I and type II molecules. In humans 54 functional keratin genes exist. They are expressed in highly specific patterns related to the epithelial type and stage of cellular differentiation. This antibody can detect high molecular weight CK10, CK14, CK15 and CK16 and low molecular weight CK19. It usually used in a cytokeratin cocktail with type II cytokeratin antibody.

Immunogen: A portion of amino acids 100-200 from Type I Cytokeratins was used as the immunogen for the recombinant Type I Cytokeratin antibody.

Storage: Store the recombinant Type I Cytokeratin antibody at 2-8oC (with azide) or aliquot and store at -20 °C or colder (without azide).

Localization: Cytoplasmic