Description
TXNIP Antibody | N1119-100UG | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: 0.5 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Format: Purified
Clone: N/A
Host Animal: Rabbit
Clonality: Polyclonal (rabbit origin)
Species Reactivity: Human
Application: WB
Buffer: 1X PBS, pH 7.4
Limitation: This TXNIP antibody is available for research use only.
Purity: Protein A affinity chromatography
Description: TXNIP (Thioredoxin-interacting protein), also called VDUP1 (Vitamin D3 upregulated protein 1) is a member of the Arrestin family of signal transduction proteins. It is a potent tumor suppressor, blocking tumor growth via blocking cell cycle progression, and reduced expression of TXNIP is found in many tumors. One way TXNIP exerts its tumor suppressive function is by suppressing NF-kB activation, possibly via regulation of the NF-kB subunit p65.
Immunogen: A recombinant protein fragment from the N-terminal region of human TXNIP was used as the immunogen for this antibody.
Storage: Aliquot the TXNIP antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.
