TXNIP Antibody | F47608-0.08ML

TXNIP Antibody | F47608-0.08ML | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide

Format: Antigen affinity purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Species Reactivity: Human

Application: WB, ELISA

Buffer: N/A

Limitation: This TXNIP antibody is available for research use only.

Purity: Antigen affinity

Description: TXNIP may act as an oxidative stress mediator by inhibiting thioredoxin activity or by limiting its bioavailability. Interacts with COPS5 and restores COPS5-induced suppression of CDKN1B stability, blocking the COPS5-mediated translocation of CDKN1B from the nucleus to the cytoplasm. Functions as a transcriptional repressor, possibly by acting as a bridge molecule between transcription factors and corepressor complexes, and over-expression will induce G0/G1 cell cycle arrest. Required for the maturation of natural killer cells. [UniProt]

Immunogen: A portion of amino acids 1-30 from the human protein was used as the immunogen for this TXNIP antibody.

Storage: Aliquot the TXNIP antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.