Description
Tubastatin A hydrochloride | 27108 | Gentaur US, UK & Europe Disrtribition
Category: Deacetylase/Inhibitors / Activators
Application: N/A
Background: N/A
Description: Tubastatin A is a potent HDAC6 inhibitor. It demonstrates over 1,000-fold selectivity against all other HDAC isoforms (IC50 >16 µM), excluding HDAC8 (IC50 = 0.9 µM). Tubastatin A induces a-tubulin hyperacetylation at 2.5 µM in primary cortical neuron cultures. In a model of oxidative stress induced by glutathione depletion, it displays dose-dependent neuronal protection of primary cortical neuron cultures at 5-10 µM.
Product Type: Inhibitor
Shippement Condition: -20°C
