TSG101 Antibody | F54200-0.2ML

TSG101 Antibody | F54200-0.2ML | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide

Format: Purified

Clone: 1883CT788.47.15.46

Host Animal: Mouse

Clonality: Monoclonal (mouse origin)

Species Reactivity: Human

Application: WB

Buffer: N/A

Limitation: This TSG101 antibody is available for research use only.

Purity: Protein G purified

Description: Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Binds to ubiquitinated cargo proteins and is required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies (MVBs). Mediates the association between the ESCRT-0 and ESCRT-I complex. Required for completion of cytokinesis; the function requires CEP55. May be involved in cell growth and differentiation. Acts as a negative growth regulator. Involved in the budding of many viruses through an interaction with viral proteins that contain a late-budding motif P-[ST]-A-P. This interaction is essential for viral particle budding of numerous retroviruses.

Immunogen: Recombinant human TSG101 protein was used as the immunogen for the TSG101 antibody.

Storage: Aliquot the TSG101 antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.