Description
TSC2 Antibody | R31543 | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: 0.5mg/ml if reconstituted with 0.2ml sterile DI water
Format: Antigen affinity purified
Clone: N/A
Host Animal: Rabbit
Clonality: Polyclonal (rabbit origin)
Species Reactivity: Human, Mouse, Rat
Application: WB, IHC-P
Buffer: N/A
Limitation: This TSC2 antibody is available for research use only.
Purity: Antigen affinity
Description: Tuberous sclerosis 2, also known as TSC2 or Tuberin is a protein that is in humans. Mutations in this gene lead to tuberous sclerosis complex. TSC2 is believed to be a tumor suppressor and is able to stimulate specific GTPases. It associates with hamartin in a cytosolic complex, possibly acting as a chaperone forHamartin. TSC2 is involved in microtubule-mediated protein transport, but this seems to be due to unregulated mTOR signaling. It stimulates weakly the intrinsic GTPase activity of the Ras-related proteins RAP1A andRAB5in vitro.
Immunogen: Human partial recombinant protein (AA 1611-1807) was used as the immunogen for this TSC2 antibody.
Storage: The lyophilized TSC2 antibody can be stored at 4oC to -20 °C. After reconstitution, aliquot and store at -20 °C. Avoid repeated freeze/thaws.
