TRP1 / Tyrosinase-Related Protein-1 Antibody | V8898SAF-100UG

TRP1 / Tyrosinase-Related Protein-1 Antibody | V8898SAF-100UG | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: 1 mg/ml in 1X PBS; BSA free, sodium azide free

Format: Purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Species Reactivity: Human

Application: IHC-P

Buffer: N/A

Limitation: This Tyrosinase-Related Protein-1 antibody is available for research use only.

Purity: Protein A affinity

Description: It reacts with a 75kDa melanocyte-specific gene product, identified as Tyrosinase-related protein-1 (TRP-1). It is involved in melanin synthesis. TRP1 is present on the melanosomal membranes of melanoma, normal melanocytes and nevi.Recent evidence suggests that TRP-1 is involved in maintaining stability of tyrosinase protein and modulating its catalytic activity. TRP-1 is also involved in maintenance of melanosome ultrastructure and affects melanocyte proliferation and cell death.

Immunogen: Recombinant human TYRP1 protein was used as the immunogen for the Tyrosinase-Related Protein-1 antibody.

Storage: Aliquot the Tyrosinase-Related Protein-1 antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.