Description
TRP1 / Tyrosinase-Related Protein-1 Antibody | V8146-20UG | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: 0.2 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Format: Purified
Clone: TYRP1/3281
Host Animal: Mouse
Clonality: Monoclonal (mouse origin)
Species Reactivity: Human
Application: ELISA, IHC-P
Buffer: N/A
Limitation: This Tyrosinase-Related Protein-1 antibody is available for research use only.
Purity: Protein G affinity chromatography
Description: It reacts with a 75kDa melanocyte-specific gene product, identified as Tyrosinase-related protein-1 (TRP-1). It is involved in melanin synthesis. TRP1 is present on the melanosomal membranes of melanoma, normal melanocytes and nevi.Recent evidence suggests that TRP-1 is involved in maintaining stability of tyrosinase protein and modulating its catalytic activity. TRP-1 is also involved in maintenance of melanosome ultrastructure and affects melanocyte proliferation and cell death.
Immunogen: A recombinant human partial protein (amino acids 257-377) was used as the immunogen for this TRP1 antibody.
Storage: Store the Tyrosinase-Related Protein-1 antibody at 2-8oC (with azide) or aliquot and store at -20 °C or colder (without azide).
