TRP1 / Tyrosinase-Related Protein-1 Antibody | V7273-20UG

TRP1 / Tyrosinase-Related Protein-1 Antibody | V7273-20UG | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide

Format: Purified

Clone: TYRP1/1564R

Host: Rabbit

Clonality: Recombinant Rabbit Monoclonal

Isotype: Rabbit IgG, kappa

Species Reactivity: Human

Application: IHC-P

Application Details: Immunohistochemistry (FFPE): 1-2ug/ml for 30 min at RT

Application Note: The optimal dilution of the recombinant TYRP1 antibody for each application should be determined by the researcher.

Purity: Protein A affinity chromatography

Description: Tyrosinase-Related Protein-1 / TYRP1 / TRP1 is involved in melanin synthesis. It is present on the melanosomal membranes of melanoma, normal melanocytes and nevi. Recent evidence suggests that TRP1 is involved in maintaining stability of tyrosinase protein and modulating its catalytic activity. It is also involved in maintenance of melanosome ultrastructure and affects melanocyte proliferation and cell death.

Immunogen: Human recombinant protein used as the immunogen for this recombinant TYRP1 antibody.

Storage: Store the recombinant TYRP1 antibody at 2-8oC (with azide) or aliquot and store at -20 °C or colder (without azide).

Localization: Cytoplasmic