Description
TRP1 / Tyrosinase-Related Protein-1 Antibody | V7273-20UG | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
Format: Purified
Clone: TYRP1/1564R
Host: Rabbit
Clonality: Recombinant Rabbit Monoclonal
Isotype: Rabbit IgG, kappa
Species Reactivity: Human
Application: IHC-P
Application Details: Immunohistochemistry (FFPE): 1-2ug/ml for 30 min at RT
Application Note: The optimal dilution of the recombinant TYRP1 antibody for each application should be determined by the researcher.
Purity: Protein A affinity chromatography
Description: Tyrosinase-Related Protein-1 / TYRP1 / TRP1 is involved in melanin synthesis. It is present on the melanosomal membranes of melanoma, normal melanocytes and nevi. Recent evidence suggests that TRP1 is involved in maintaining stability of tyrosinase protein and modulating its catalytic activity. It is also involved in maintenance of melanosome ultrastructure and affects melanocyte proliferation and cell death.
Immunogen: Human recombinant protein used as the immunogen for this recombinant TYRP1 antibody.
Storage: Store the recombinant TYRP1 antibody at 2-8oC (with azide) or aliquot and store at -20 °C or colder (without azide).
Localization: Cytoplasmic
