Description
TROP2 - CHO-K1 Recombinant Cell Line | 78099 | Gentaur US, UK & Europe Disrtribition
Category: Cell Signaling/Cell Line
Application: 1. Useful for screening and validating antibodies against Trop2 and anti-Trop2 CAR-T for immunotherapy research and drug discovery.
2. Useful for Trop2 binding assays to screening for Trop2 ligands.
Background: Trophoblast cell-surface antigen 2 (TROP-2), also referred to as tumor associated calcium signal transducer 2 (TACSTD2), GA733-1 or M1S1, is a cell surface glycoprotein that is highly expressed in a variety of solid cancers, yet has low expression in normal cells. Through a variety of signaling pathways, TROP2 regulates cancer growth and metastasis and is a favorable target for antibody drug conjugates (ADC) and immunotherapy.
Description: Recombinant CHO-K1 cells expressing the cell surface glycoprotein TROP2 (Trophoblast cell-surface antigen 2); ref. seq. NM_002353.2.
Product Type: Cell Line
Shippement Condition: -80°C
