Description
TRKC Kinase Assay Kit | 78528 | Gentaur US, UK & Europe Disrtribition
Category: Kinase/Assay Kit
Application: Study enzyme kinetics and screen small molecular inhibitors for drug discovery and high throughput (HTS) applications.
Background: Tropomyosin receptor kinase C (TRKC), also known as neurotrophic tyrosine kinase receptor type 3, is a member of the receptor tyrosine kinase family that mediates neurotrophin-activated signaling. TRKC is a functional coordinator in the activation of a host of signaling cascades including the mitogen-activated protein kinase (MAPK) pathway that leads to cell differentiation. Most recently, it has been shown that TRKC levels in hippocampal neurons dictate TRKC-mediated synapse density. TRKC expression levels are known to play a role in tumorigenesis as well as neurodegenerative diseases. Studies involving TRKC may lead to further understanding of disease pathology and to therapeutic treatments.
Description: The Tropomyosin receptor kinase C (TRKC) Kinase Assay Kit is designed to measure TRKC kinase activity for screening and profiling applications using Kinase-Glo® MAX as a detection reagent.
Product Type: Assay Kit
Shippement Condition: -80°C
