Description
TrkC Antibody | F50686-0.08ML | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide
Format: Purified
Clone: N/A
Host Animal: Rabbit
Clonality: Polyclonal (rabbit origin)
Species Reactivity: Human
Application: IHC, WB, ELISA
Buffer: N/A
Limitation: This TrkC antibody is available for research use only.
Purity: Purified
Description: TRKC, a member of the insuline receptor subfamily of Tyr protein kinases, is a receptor for neurotrophin-3 (NT-3). Known substrates for the TRK receptors are SHC, PI-3 kinase, and PLCG1. The different isoforms do not have identical signaling properties. The protein is widely expressed, mainly in the nervous tissue. The isoform B is expressed in a relatively large amount in the adult brain comparatively to fetal brain. TRKC is subject to ligand-mediated auto-phosphorylation. The protein structure contains 2 immunoglobulin-like C2-type domains and 2 leucine-rich (LRR) repeats.
Immunogen: This TrkC antibody was produced from rabbits immunized with a his tag recombinant protein of human TrkC.
Storage: Aliquot the TrkC antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.
