TrkA Antibody (phospho-Y791) | F48462-0.08ML

TrkA Antibody (phospho-Y791) | F48462-0.08ML | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide

Format: Antigen affinity purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Species Reactivity: Human

Application: DB, ELISA

Buffer: N/A

Limitation: This phospho-TrkA antibody is available for research use only.

Purity: Antigen affinity

Description: TrkA is a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in the TrkA gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, mental retardation and cancer.

Immunogen: This phospho-TrkA antibody was produced from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding pY791 of human TrkA.

Storage: Aliquot the phospho-TrkA antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.