Description
TrkA Antibody (NTRK1) | F50683-0.08ML | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide
Format: Antigen affinity purified
Clone: N/A
Host Animal: Rabbit
Clonality: Polyclonal (rabbit origin)
Species Reactivity: Human
Application: WB, FACS, IHC, ELISA
Buffer: N/A
Limitation: This TrkA antibody is available for research use only.
Purity: Antigen affinity
Description: TRKA (also known as NTRK1)is a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in the TRKA gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, mental retardation and cancer.
Immunogen: A portion of amino acids 769-796 from the human protein was used as the immunogen for this TrkA antibody.
Storage: Aliquot the TrkA antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.