Description
TRIO Antibody / Triple functional domain protein | R31840 | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: 0.5mg/ml if reconstituted with 0.2ml sterile DI water
Format: Antigen affinity purified
Clone: N/A
Host Animal: Rabbit
Clonality: Polyclonal (rabbit origin)
Species Reactivity: Human, Mouse, Rat
Application: WB
Buffer: N/A
Limitation: This TRIO antibody is available for research use only.
Purity: Antigen affinity
Description: Triple functional domain protein is a protein that in humans is encoded by the TRIO gene. This gene encodes a large protein that functions as a GDP to GTP exchange factor. This protein promotes the reorganization of the actin cytoskeleton, thereby playing a role in cell migration and growth. Additionally, the TRIO protein contains 3 functional domains: a serine/threonine kinase domain and 2 guanine nucleotide exchange factor (GEF) domains for the family of Rho-like GTPases, specific for Rac1 and RhoA, respectively. These domains suggest that this enzyme may play a key role in several signaling pathways that control cell proliferation.
Immunogen: Amino acids QLRIFERDAIDIISDLESWNDELSQQMNDFDTEDLTIAEQRLQH of human TRIO were used as the immunogen for the TRIO antibody.
Storage: After reconstitution, the TRIO antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20 °C. Avoid repeated freezing and thawing.
