Description
Transglutaminase 2 Antibody | F54953-0.08ML | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide
Format: Purified
Clone: N/A
Host Animal: Rabbit
Clonality: Polyclonal (rabbit origin)
Species Reactivity: Human
Application: WB, IF, IHC-P
Buffer: N/A
Limitation: This Protein-glutamine gamma-glutamyltransferase 2 antibody is available for research use only.
Purity: Purified
Description: Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon-gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. TGM2 acts as a monomer, is induced by retinoic acid, and appears to be involved in apoptosis. It has been identified as the autoantigen implicated in celiac disease.
Immunogen: A portion of amino acids 429-458 from the human protein was used as the immunogen for the Protein-glutamine gamma-glutamyltransferase 2 antibody.
Storage: Aliquot the Protein-glutamine gamma-glutamyltransferase 2 antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.