Transferrin Receptor Antibody / TFRC / CD71 | V8479-100UG

Transferrin Receptor Antibody / TFRC / CD71 | V8479-100UG | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide

Format: Purified

Clone: TFRC/3630

Host Animal: Mouse

Clonality: Monoclonal (mouse origin)

Species Reactivity: Human

Application: IHC-P

Buffer: N/A

Limitation: This CD71 antibody is available for research use only.

Purity: Protein G affinity chromatography

Description: It recognizes a ~90-95kDa protein which is identified as cell surface transferrin receptor (CD71), a disulfide-bonded homodimeric glycoprotein of 180-190kDa (Workshop IV). This MAb is highly specific to CD71 and shows no cross-reaction with other related proteins. Ligand for transferrin receptor is the serum iron transport protein, transferrin. This receptor is broadly distributed in carcinomas, sarcomas, leukemias, and lymphomas. CD71/Transferrin receptor has been reported to be associated with cell proliferation in both normal and neoplastic tissues and useful in predicting clinical behavior or response to therapy in a number of malignancies including breast cancer.

Immunogen: The acute myeloid leukemia cell line KG1 was used as the immunogen for the CD71 antibody.

Storage: Store the CD71 antibody at 2-8oC (with azide) or aliquot and store at -20 °C or colder (without azide).