Transferrin Receptor Antibody / TFRC / CD71 | V2261-100UG

Transferrin Receptor Antibody / TFRC / CD71 | V2261-100UG | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide

Format: Purified

Clone: 66IG10

Host Animal: Mouse

Clonality: Monoclonal (mouse origin)

Species Reactivity: Human

Application: ELISA, FACS, IF

Buffer: N/A

Limitation: This Transferrin receptor antibody is available for research use only.

Purity: Protein G affinity chromatography

Description: This antibody recognizes a ~85-95kDa protein which is identified as cell surface Transferrin receptor (CD71), a disulfide-bonded homodimeric glycoprotein of 180-190kDa. The antibody is highly specific to transferrin receptor and shows no cross-reaction with other related proteins. Its epitope is localized in the extracellular domain of transferrin receptor. Its ligand is the serum iron transport protein, transferrin. This receptor is broadly distributed in carcinomas, sarcomas, leukemias, and lymphomas. Transferrin receptor has been reported to be associated with cell proliferation in both normal and neoplastic tissues and useful in predicting clinical behavior or response to therapy in a number of malignancies including breast cancer.

Immunogen: Recombinant human protein was used as the immunogen for this Transferrin receptor antibody.

Storage: Store the Transferrin receptor antibody at 2-8oC (with azide) or aliquot and store at -20 °C or colder (without azide).