TRAIL R2 Antibody / DR5 | RQ4711

TRAIL R2 Antibody / DR5 | RQ4711 | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: Antibody in PBS with 0.02% sodium azide and 50% glycerol

Format: Purified

Clone: ABFC-20

Host Animal: Rabbit

Clonality: Rabbit Monoclonal

Species Reactivity: Human

Application: WB

Buffer: N/A

Limitation: This DR5 antibody is available for research use only.

Purity: Affinity purified

Description: The protein encoded by the TNFRSF10B is a member of the TNF-receptor superfamily, and contains an intracellular death domain. Death receptor 5 can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces an apoptosis signal. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. [RefSeq]

Immunogen: A synthetic peptide specific to human DR5 / TNFRSF10B was used as the immunogen for the DR5 antibody.

Storage: Store the DR5 antibody at -20 °C.