Description
TRAIL R2 Antibody / DR5 | RQ4711 | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: Antibody in PBS with 0.02% sodium azide and 50% glycerol
Format: Purified
Clone: ABFC-20
Host Animal: Rabbit
Clonality: Rabbit Monoclonal
Species Reactivity: Human
Application: WB
Buffer: N/A
Limitation: This DR5 antibody is available for research use only.
Purity: Affinity purified
Description: The protein encoded by the TNFRSF10B is a member of the TNF-receptor superfamily, and contains an intracellular death domain. Death receptor 5 can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces an apoptosis signal. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. [RefSeq]
Immunogen: A synthetic peptide specific to human DR5 / TNFRSF10B was used as the immunogen for the DR5 antibody.
Storage: Store the DR5 antibody at -20 °C.
