Description
TRAF4 Antibody | R31116 | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: 0.5mg/ml if reconstituted with 0.2ml sterile DI water
Format: Antigen affinity purified
Clone: N/A
Host Animal: Rabbit
Clonality: Polyclonal (rabbit origin)
Species Reactivity: Human, Mouse, Rat
Application: WB, IHC-P
Buffer: N/A
Limitation: This TRAF4 antibody is available for research use only.
Purity: Antigen affinity
Description: TNF Receptor-Associated Factor 4, also called CART1 or MLN62, is a protein that in humans is encoded by the TRAF4 gene. It is a member of the TNF receptor associated factor(TRAF) family, a family of scaffold proteins. Tomasetto et al.(1995) identified genes that are overexpressed in breast cancer by differential screening of cDNAs from breast cancer-derived metastatic axillary lymph nodes. The TRAF4 cDNA, which they designated MLN62, was mapped to 17q11-q12 by radioisotopic in situ hybridization. To investigate the biologic function of TRAF4, Regnier et al.(2002) generated Traf4-deficient mice by gene disruption.
Immunogen: An amino acid sequence from the C-terminus of human TNF Receptor-Associated Factor 4 (PKFISHQDIRKRNYVRDD) was used as the immunogen for this TRAF4 antibody (100% homologous in human, mouse and rat).
Storage: After reconstitution, the TRAF4 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20 °C. Avoid repeated freezing and thawing.
