Description
TPX2 Polyclonal Antibody | E-AB-17130 | Gentaur US, UK & Europe Disrtribition
Reactivity: Human, Mouse
Host: Rabbit
Isotype: IgG
Application: WB, IHC, ELISA
Research Area: Cancer, Cell biology, Epigenetics and Nuclear Signaling
Background: Spindle assembly factor. Required for normal assembly of mitotic spindles. Required for normal assembly of microtubules during apoptosis. Required for chromatin and/or kinetochore dependent microtubule nucleation. Mediates AURKA localization to spindle microtubules. Activates AURKA by promoting its autophosphorylation at 'Thr-288' and protects this residue against dephosphorylation.
Lead Time: 7~10 days
Concentration: 0.7 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: Fusion protein of human TPX2
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification: Affinity purification
Dilution: WB 1:500-2000, IHC 1:30-150, ELISA 1:2000-5000
Conjugation: Unconjugated
Calculated Molecular Weight: 86 kDa
Observed Molecular Weight: N/A
Clonality: Polyclonal