TPX2 Polyclonal Antibody | E-AB-17130

TPX2 Polyclonal Antibody | E-AB-17130 | Gentaur US, UK & Europe Disrtribition

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Application: WB, IHC, ELISA

Research Area: Cancer, Cell biology, Epigenetics and Nuclear Signaling

Background: Spindle assembly factor. Required for normal assembly of mitotic spindles. Required for normal assembly of microtubules during apoptosis. Required for chromatin and/or kinetochore dependent microtubule nucleation. Mediates AURKA localization to spindle microtubules. Activates AURKA by promoting its autophosphorylation at 'Thr-288' and protects this residue against dephosphorylation.

Lead Time: 7~10 days

Concentration: 0.7 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Fusion protein of human TPX2

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification: Affinity purification

Dilution: WB 1:500-2000, IHC 1:30-150, ELISA 1:2000-5000

Conjugation: Unconjugated

Calculated Molecular Weight: 86 kDa

Observed Molecular Weight: N/A

Clonality: Polyclonal