TPX2 Antibody / Targeting protein for Xklp2 | F53942-0.2ML

TPX2 Antibody / Targeting protein for Xklp2 | F53942-0.2ML | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide

Format: Purified

Clone: 1696CT464.66.9

Host Animal: Mouse

Clonality: Monoclonal (mouse origin)

Species Reactivity: Human

Application: WB

Buffer: N/A

Limitation: This TPX2 antibody is available for research use only.

Purity: Protein G affinity chromatography

Description: Targeting protein for Xklp2 is a spindle assembly factor. Required for normal assembly of mitotic spindles. Required for normal assembly of microtubules during apoptosis. Required for chromatin and/or kinetochore dependent microtubule nucleation. Mediates AURKA localization to spindle microtubules. Activates AURKA by promoting its autophosphorylation at 'Thr-288' and protects this residue against dephosphorylation.

Immunogen: A partial recombinant protein corresponding to amino acids 1-531 from the human protein was used as the immunogen for the TPX2 antibody.

Storage: Aliquot the TPX2 antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.