TPX2 Antibody (p100) | F40193-0.08ML

TPX2 Antibody (p100) | F40193-0.08ML | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: In 1X PBS pH 7.4 with 0.09% sodium azide

Format: Purified

Clone: 19AT953.286.93

Host Animal: Mouse

Clonality: Monoclonal (mouse origin)

Species Reactivity: Human, Mouse

Application: WB, ELISA

Buffer: N/A

Limitation: This TPX2 antibody is available for research use only.

Purity: Purified

Description: TPX2 is a spindle assembly factor. Required for normal assembly of mitotic spindles. Required for normal assembly of microtubules during apoptosis. Required for chromatin and/or kinetochore dependent microtubule nucleation. Mediates AURKA localization to spindle microtubules. Activates AURKA by promoting its autophosphorylation at 'Thr-288' and protects this residue against dephosphorylation. [UniProt]

Immunogen: A KLH conjugated synthetic peptide from the human protein was used as immunogen for this TPX2 antibody.

Storage: Aliquot the TPX2 antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.