Description
TPX2 Antibody (p100) | F40192-0.08ML | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: In 1X PBS pH 7.4 with 0.09% sodium azide
Format: Purified
Clone: 19AT738.292
Host Animal: Mouse
Clonality: Monoclonal (mouse origin)
Species Reactivity: Human, Mouse
Application: WB, ELISA
Buffer: N/A
Limitation: This p100 antibody is available for research use only.
Purity: Purified
Description: p100 is a spindle assembly factor. Required for normal assembly of mitotic spindles. Required for normal assembly of microtubules during apoptosis. Required for chromatin and/or kinetochore dependent microtubule nucleation. Mediates AURKA localization to spindle microtubules. Activates AURKA by promoting its autophosphorylation at 'Thr-288' and protects this residue against dephosphorylation. [UniProt]
Immunogen: A KLH conjugated synthetic peptide from the human protein was used as immunogen for this p100 antibody.
Storage: Aliquot the p100 antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.
