TP53 Polyclonal Antibody | E-AB-40494

TP53 Polyclonal Antibody | E-AB-40494 | Gentaur US, UK & Europe Disrtribition

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Application: WB, IHC-P

Research Area: Cancer, Cell Biology, Epigenetics and Nuclear Signaling

Background: TP53, also named as P53 and NY-CO-13, belongs to the p53 family. It has 9 isoforms. In SDS-Page, the MW is about 53kd. TP53 acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. It is involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. The antibody reacts specifically with 53 kDa protein.

Lead Time: 7~10 days

Concentration: 1mg/mL

Storage: Store at -20℃. Avoid freeze / thaw cycles.

Immunogen: Synthetic peptide of Human Cellular tumor antigen p53

Buffer: PBS with 0.05% Proclin300, 50% glycerol, pH7.3.

Purification: Antigen Affinity Purification

Dilution: WB 1:1000-1:3000, IHC 1:50-1:200

Conjugation: Unconjugated

Calculated Molecular Weight: 53 kDa

Observed Molecular Weight: 53 kDa

Clonality: Polyclonal