Description
Topoisomerase II alpha Antibody / TOP2A | V9302SAF-100UG | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: 1 mg/ml in 1X PBS; BSA free, sodium azide free
Format: Purified
Clone: rTOP2A/6569
Host: Mouse
Clonality: Recombinant Mouse Monoclonal
Isotype: Mouse IgG2a, kappa
Species Reactivity: Human, Mouse
Application: WB, IHC-P
Application Details: Western blot: 1-2ug/ml,Immunohistochemistry (FFPE): 0.5-1ug/ml
Application Note: Optimal dilution of the recombinant TOP2A antibody should be determined by the researcher.
Purity: Protein A/G affinity
Description: It recognizes a 170kDa protein, which is identified as topoisomerase II is also implicated in drug resistance of tumor cells and has been shown to be over-expressed in many human cancers. Decreased expression of Topo IIa is the predominant mechanism of resistance to several chemotherapeutic agents.
Immunogen: A portion of amino acids 1352-1493 was used as the immunogen for the recombinant TOP2A antibody.
Storage: Aliquot the recombinant TOP2A antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.
Localization: Nuclear
