Topoisomerase II alpha Antibody / TOP2A | V9302-100UG

Topoisomerase II alpha Antibody / TOP2A | V9302-100UG | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide

Format: Purified

Clone: rTOP2A/6569

Host: Mouse

Clonality: Recombinant Mouse Monoclonal

Isotype: Mouse IgG2a, kappa

Species Reactivity: Human, Mouse

Application: WB, IHC-P

Application Details: Western blot: 1-2ug/ml,Immunohistochemistry (FFPE): 0.5-1ug/ml

Application Note: Optimal dilution of the recombinant TOP2A antibody should be determined by the researcher.

Purity: Protein A/G affinity

Description: It recognizes a 170kDa protein, which is identified as topoisomerase II is also implicated in drug resistance of tumor cells and has been shown to be over-expressed in many human cancers. Decreased expression of Topo IIa is the predominant mechanism of resistance to several chemotherapeutic agents.

Immunogen: A portion of amino acids 1352-1493 was used as the immunogen for the recombinant TOP2A antibody.

Storage: Aliquot the recombinant TOP2A antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.

Localization: Nuclear