Topoisomerase II alpha Antibody / TOP2A | V8971-20UG

Topoisomerase II alpha Antibody / TOP2A | V8971-20UG | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide

Format: Purified

Clone: rTOP2A/6629

Host: Mouse

Clonality: Recombinant Mouse Monoclonal

Isotype: Mouse IgG1, kappa

Species Reactivity: Human, Mouse

Application: IHC-P

Application Details: Immunohistochemistry (FFPE): 0.5-1ug/ml

Application Note: Optimal dilution of the recombinant Topoisomerase II alpha antibody should be determined by the researcher.

Purity: Protein A/G affinity

Description: Key decatenating enzyme that alters DNA topology by binding to two double-stranded DNA molecules, generating a double-stranded break in one of the strands, passing the intact strand through the broken strand, and re-ligating the broken strand. [UniProt]

Immunogen: A portion of amino acids 1352-1493 was used as the immunogen for the recombinant Topoisomerase II alpha antibody.

Storage: Aliquot the recombinant Topoisomerase II alpha antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.

Localization: Nuclear