Description
Topoisomerase II alpha Antibody / TOP2A | V8971-20UG | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Format: Purified
Clone: rTOP2A/6629
Host: Mouse
Clonality: Recombinant Mouse Monoclonal
Isotype: Mouse IgG1, kappa
Species Reactivity: Human, Mouse
Application: IHC-P
Application Details: Immunohistochemistry (FFPE): 0.5-1ug/ml
Application Note: Optimal dilution of the recombinant Topoisomerase II alpha antibody should be determined by the researcher.
Purity: Protein A/G affinity
Description: Key decatenating enzyme that alters DNA topology by binding to two double-stranded DNA molecules, generating a double-stranded break in one of the strands, passing the intact strand through the broken strand, and re-ligating the broken strand. [UniProt]
Immunogen: A portion of amino acids 1352-1493 was used as the immunogen for the recombinant Topoisomerase II alpha antibody.
Storage: Aliquot the recombinant Topoisomerase II alpha antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.
Localization: Nuclear