Description
Topoisomerase II alpha Antibody / TOP2A | V7245-100UG | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
Format: Purified
Clone: TPM2A-1
Host Animal: Mouse
Clonality: Monoclonal (mouse origin)
Species Reactivity: Human
Application: WB, IF, IHC
Buffer: N/A
Limitation: This TOP2A antibody is available for research use only.
Purity: Protein G affinity chromatography
Description: This mAb recognizes a 170kDa protein which is identified as Topoisomerase IIa, and shows no cross-reaction with Topoisomerase IIb or I. Topo IIa plays important roles in synthesis and transcription of DNA as well as chromosomal segregation during mitosis. It is reported to be a sensitive and specific marker of late S-, G2- & M-phases in transformed and developmentally regulated normal cells. Topo IIa is also implicated in drug resistance of tumor cells.
Immunogen: Human recombinant partial protein (amino acids 1352-1493) was used as the immunogen for this TOP2A antibody.
Storage: Store the TOP2A antibody at 2-8oC (with azide) or aliquot and store at -20 °C or colder (without azide).
