Topoisomerase II alpha Antibody / TOP2A | V3442SAF-100UG

Topoisomerase II alpha Antibody / TOP2A | V3442SAF-100UG | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: 1 mg/ml in 1X PBS; BSA free, sodium azide free

Format: Purified

Clone: TOP2A/1362

Host Animal: Mouse

Clonality: Monoclonal (mouse origin)

Species Reactivity: Human

Application: WB, IF, IHC-P

Buffer: N/A

Limitation: This TOP2A antibody is available for research use only.

Purity: Protein G affinity chromatography

Description: This mAb recognizes an ~170kDa protein which is identified as Topoisomerase IIa, and shows no cross-reaction with Topoisomerase IIb or I. Topo IIa plays important roles in synthesis and transcription of DNA as well as chromosomal segregation during mitosis. It is reported to be a sensitive and specific marker of late S-, G2- & M-phases in transformed and developmentally regulated normal cells. Topo IIa is also implicated in drug resistance of tumor cells.

Immunogen: Amino acids 1352-1493 from the human protein were used as the immunogen for this TOP2A antibody.

Storage: Store the TOP2A antibody at 2-8oC (with azide) or aliquot and store at -20 °C or colder (without azide).