Description
Topoisomerase II alpha Antibody / TOP2A | F55028-0.4ML | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide
Format: Purified
Clone: N/A
Host Animal: Rabbit
Clonality: Polyclonal (rabbit origin)
Species Reactivity: Human
Application: IF, IHC-P, WB
Buffer: N/A
Limitation: This Topoisomerase II alpha antibody is available for research use only.
Purity: Antigen affinity purified
Description: TOP2A encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This nuclear enzyme is involved in processes such as chromosome condensation, chromatid separation, and the relief of torsional stress that occurs during DNA transcription and replication. It catalyzes the transient breaking and rejoining of two strands of duplex DNA which allows the strands to pass through one another, thus altering the topology of DNA.
Immunogen: A portion of amino acids 1167-1196 from the human protein was used as the immunogen for the Topoisomerase II alpha antibody.
Storage: Aliquot the Topoisomerase II alpha antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.