TNFR1-associated DEATH domain protein Antibody / TRADD | F54628-0.4ML

TNFR1-associated DEATH domain protein Antibody / TRADD | F54628-0.4ML | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide

Format: Purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Species Reactivity: Human

Application: IF, FACS, IHC-P, WB

Buffer: N/A

Limitation: This TNFR1-associated DEATH domain protein antibody is available for research use only.

Purity: Antigen affinity purified

Description: The protein encoded by this gene is a death domain containing adaptor molecule that interacts with TNFRSF1A/TNFR1 and mediates programmed cell death signaling and NF-kappaB activation. This protein binds adaptor protein TRAF2, reduces the recruitment of inhibitor-of-apoptosis proteins (IAPs) by TRAF2, and thus suppresses TRAF2 mediated apoptosis. This protein can also interact with receptor TNFRSF6/FAS and adaptor protein FADD/MORT1, and is involved in the Fas-induced cell death pathway. [provided by RefSeq].

Immunogen: A portion of amino acids 126-151 from the human protein was used as the immunogen for the TRADD antibody.

Storage: Aliquot the TRADD antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.