Description
TNFR1-associated DEATH domain protein Antibody / TRADD | F54628-0.08ML | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide
Format: Purified
Clone: N/A
Host Animal: Rabbit
Clonality: Polyclonal (rabbit origin)
Species Reactivity: Human
Application: IF, FACS, IHC-P, WB
Buffer: N/A
Limitation: This TNFR1-associated DEATH domain protein antibody is available for research use only.
Purity: Antigen affinity purified
Description: The protein encoded by this gene is a death domain containing adaptor molecule that interacts with TNFRSF1A/TNFR1 and mediates programmed cell death signaling and NF-kappaB activation. This protein binds adaptor protein TRAF2, reduces the recruitment of inhibitor-of-apoptosis proteins (IAPs) by TRAF2, and thus suppresses TRAF2 mediated apoptosis. This protein can also interact with receptor TNFRSF6/FAS and adaptor protein FADD/MORT1, and is involved in the Fas-induced cell death pathway. [provided by RefSeq].
Immunogen: A portion of amino acids 126-151 from the human protein was used as the immunogen for the TRADD antibody.
Storage: Aliquot the TRADD antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.
