TMEPAI Antibody / PMEPA1 | V9209-20UG

TMEPAI Antibody / PMEPA1 | V9209-20UG | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide

Format: Purified

Clone: PMEPA1/6421R

Host: Rabbit

Clonality: Recombinant Rabbit Monoclonal

Isotype: Rabbit IgG

Species Reactivity: Human

Application: IHC-P

Application Details: Immunohistochemistry (FFPE): 1-2ug/ml

Application Note: Optimal dilution of the recombinant TMEPAI antibody should be determined by the researcher.

Purity: Protein A/G affinity

Description: PMEPA1 (prostate transmembrane protein, androgen induced 1 is a 287 amino acid single-pass membrane protein that contains WW-binding motifs and localizes to the cell membrane. Expressed at high levels in prostate, kidney and ovary, PMEPA1 interacts with NEDD4 and may play a role in regulating AR (androgen receptor) levels, specifically in prostate cells. Down regulation of PMEPA1 is observed in prostate tumors, suggesting that PMEPA1 may exhibit activity as a tumor suppressor. Overexpression of this protein may play a role in multiple types of cancer.

Immunogen: Recombinant full-length human PMEPA1/TMEPAI protein was used as the immunogen for the recombinant TMEPAI antibody.

Storage: Aliquot the recombinant TMEPAI antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.

Localization: Cell surface, Cytoplasm