TMEPAI Antibody / PMEPA1 | V7329SAF-100UG

TMEPAI Antibody / PMEPA1 | V7329SAF-100UG | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: 1 mg/ml in 1X PBS; BSA free, sodium azide free

Format: Purified

Clone: PMEPA1/2698

Host Animal: Mouse

Clonality: Monoclonal (mouse origin)

Species Reactivity: Human

Application: IHC-P

Buffer: N/A

Limitation: This TMEPAI antibody is available for research use only.

Purity: Protein G affinity chromatography

Description: PMEPA1 (prostate transmembrane protein, androgen induced 1), or TMEPAI (Transmembrane prostate androgen induced protein) is a 287 amino acid single-pass membrane protein that contains WW-binding motifs and localizes to the cell membrane. Expressed at high levels in prostate, kidney and ovary, PMEPA1/TMEPAI interacts with NEDD4 and may play a role in regulating AR (androgen receptor) levels, specifically in prostate cells. Down regulation of TMEPAI is observed in prostate tumors, suggesting that TMEPAI may exhibit activity as a tumor suppressor. Overexpression of this protein may play a role in multiple types of cancer.

Immunogen: Full-length recombinant human protein was used as the immunogen for the TMEPAI antibody.

Storage: Store the TMEPAI antibody at 2-8oC (with azide) or aliquot and store at -20 °C or colder (without azide).