TMED10 Polyclonal Antibody | E-AB-19178

TMED10 Polyclonal Antibody | E-AB-19178 | Gentaur US, UK & Europe Disrtribition

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Application: WB, IHC, ELISA

Research Area: Cancer, Neuroscience, Signal transduction

Background: This gene is a member of the EMP24/GP25L/p24 family and encodes a protein with a GOLD domain. This type I membrane protein is localized to the plasma membrane and golgi cisternae and is involved in vesicular protein trafficking. The protein is also a member of a heteromeric secretase complex and regulates the complex's gamma-secretase activity without affecting its epsilon-secretase activity. Mutations in this gene have been associated with early-onset familial Alzheimer's disease. This gene has a pseudogene on chromosome 8.

Lead Time: 7~10 days

Concentration: 1.14 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Fusion protein of human TMED10

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification: Antigen affinity purification

Dilution: WB 1:1000-1:5000, IHC 1:50-1:200, ELISA 1:5000-1:10000

Conjugation: Unconjugated

Calculated Molecular Weight: 25 kDa

Observed Molecular Weight: Refer to figures

Clonality: Polyclonal