TLR9 Polyclonal Antibody | E-AB-70125

TLR9 Polyclonal Antibody | E-AB-70125 | Gentaur US, UK & Europe Disrtribition

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Application: IHC

Research Area: Immunology, Signal Transduction

Background: The protein encoded by this gene is a member of the Toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. Studies in mice and human indicate that this receptor mediates cellular response to unmethylated CpG dinucleotides in bacterial DNA to mount an innate immune response.

Lead Time: 7~10 days

Concentration: 1.5 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: KLH conjugated Synthetic peptide corresponding to Mouse TLR9

Buffer: PBS with 0.02% sodium azide, 1% BSA and 50% glycerol, pH7.4

Purification: Affinity purification

Dilution: IHC 1:100-1:500

Conjugation: Unconjugated

Calculated Molecular Weight: N/A

Observed Molecular Weight: N/A

Clonality: Polyclonal